Trivia

Jessica Alba had a no-nudity cause in her contract, which is why her clothes were digitally removed for her nude scenes. Alba: “No, I'll never do a nude scene. I can act sexy and wear sexy clothes but I can't go naked.”
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Danny Trejo, Jeff Fahey, Cheech Marin and Tito Larriva, who are featured in the fake trailer featured in Grindhouse (2007), reprise their roles for this film. Fahey was also featured in Planet Terror (2007), which was written, produced and directed by Robert Rodriguez, the director of this film.

This film was made because of the popularity of a fake trailer for a non-existent Machete film that was featured in the theatrical version of Grindhouse (2007), along with other fake trailers and advertisements featured in the film.

Robert Rodriguez wrote the script back in 1993 after he wrote Desperado (1995).

Actor Chris Cooper reportedly turned down a role in the movie saying "it's the most absurd thing I've ever read" after getting the script.

This marks the third time Steven Seagal and Danny Trejo have appeared together in a movie. First, briefly, in Marked for Death (1990), and again in Urban Justice (2007).

This is Danny Trejo's fifth movie appearance as Machete. The first was in Spy Kids (2001) and the rest were in its sequels.

One of the Hungarian bodyguards was played by Nimrod Antal. Antal directed Predators (2010), which was produced by Robert Rodriguez, the director of this movie. Star Danny Trejo also stars in Predators (2010).

WILHELM SCREAM: Heard during the climactic battle, when one of Lt. Stillman's men is crushed by the "low-rider" style truck.

Filmed at the same time as Predators (2010), which was originally supposed to be directed by Robert Rodriguez, who had to turn it down because he was already slated to direct this film. Instead, Rodriguez produced Predators. The sets were side-by-side. While filming Machete, they were constantly competing for daylight.